We at Clean Green Biosystems ( have developed an integrated cryo ethanol extraction process after a long research of 5 years. The extraction system comprises of ASME and cGMP complaint process equipments like Extractor, shell and tube heat exchanger, condenser, pumps and accessories. The entire process shall be operated by means of a PLC-SCADA software. The system is fixed in a SS cladded skid.

The extractor is a SS 316 jacketed vessel with a high torque agitation system with FLP motor and a gearbox, whose RPM shall be adjusted by a VFD. The bottom of the extractor is detachable by means of a hydraulic power pack which helps in the easy disposal of spent cannabis materials. A recirculation line is available using a FLP pump with VFD, to regulate the flow of miscella.

A suitable shell and tube heat exchanger is the part of the system, through which the ethanol is passed into the extractor. Liquid nitrogen is passed into the shell side of the heat exchanger which cools the ethanol to cryo temperature. This liquid nitrogen is recirculated using a liquid nitrogen transducer. The liquid nitrogen can also be passed to the jacket of the extractor to maintain the process temperature.

Frozen and size reduced cannabis plant material is charged into the extractor. The size of cannabis plant material is critical in this case. Simultaneously the cryo ethanol is sent into the extractor. The programmed PLC will switch on the agitator at a specific time. After few hours of extraction, the re circulation starts as to ensure a high efficient extraction. The integration of agitation and re circulation maximizes the extraction efficiency. Once the extraction is completed, the system comes to a standstill and the recirculation pump collects the cannabinoids rich miscella in a tank. This miscella is taken for further processing.